کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8756326 | 1596227 | 2009 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A case report of thyroid cancer showing a remarkable effect of gefitinib
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی و دندانپزشکی (عمومی)
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چکیده انگلیسی
Thyroid cancer is a common type of cancer. The most radical treatment for this type of tumor is surgical removal. Gefitinib disrupts the EGFR kinase activity. This report describes a patient with thyroid cancer who demonstrated a complete response to gefitinib. The patient was a 56-year-old woman. She had been treated for lung cancer. The lung cancer had initially disappeared following chemoradiotherapy. However, a few months later, a distant metastasis was detected on the opposite lung field. Thyroid cancer was then incidentally observed when these lesions were examined. Fine needle aspiration cytology of the thyroid tumor with ultrasonography (US) showed papillary carcinoma. Finally, all of the lesions were treated with gefitinib. Gefitinib demonstrated a remarkable effect on both the thyroid and lung lesions. The CT showed a complete resolution of the masses in the lung, neck and thyroid. The present report suggests that treatment with gefitinib is therefore an effective option for thyroid papillary carcinoma.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Auris Nasus Larynx - Volume 36, Issue 5, October 2009, Pages 623-626
Journal: Auris Nasus Larynx - Volume 36, Issue 5, October 2009, Pages 623-626
نویسندگان
Fumihiko Matsumoto, Shin Itoh, Shin-ichi Ohba, Katsuhisa Ikeda,