کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8773256 1599150 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of kidney disease on glucose handling (including genetic defects)
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Effect of kidney disease on glucose handling (including genetic defects)
چکیده انگلیسی
Reabsorption of glucose in the proximal renal tubule involves the Na+-coupled glucose cotransporter (SGLT) and the facilitative glucose transport (GLUT) multigene glucose transport families. Mutations in SLC5A2, the SGLT2 coding gene, are responsible for familial renal glucosuria (FRG), a genetic disorder characterized by glucosuria in the absence of both hyperglycemia and generalized proximal tubular dysfunction. In this paper we focus on FRG and describe other inherited and acquired clinical conditions associated with glucosuria. In addition, a brief review on the regulation of renal glucose transport in diabetes is provided.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Kidney International - Volume 79, Supplement 120, March 2011, Pages S7-S13
نویسندگان
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