کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8777665 1599447 2018 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A review of the conundrum of mild hypoxic-ischemic encephalopathy: Current challenges and moving forward
ترجمه فارسی عنوان
بازبینی مسأله ی انسفالوپاتی هیپوکسیکسیکمی خفیف: چالش های جاری و حرکت به جلو
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
چکیده انگلیسی
A review of the conundrum called mild hypoxic-ischemic encephalopathy (HIE) is provided. During the past decades, the definition of HIE has evolved to accommodate the short window of time required for the initiation of therapeutic hypothermia. Also, neurological evaluations have changed with the use of simpler staging systems that can be applied within the first 6 h of life. In this review, we discuss the challenges in the identification of newborns with “mild HIE” within 6 h after birth, the limitations in the existing early biomarkers of brain injury, and the current knowledge gaps in the long term neurodevelopmental outcomes of infants diagnosed with mild HIE. Progress in the understanding of mild HIE and its sequelae continues to be hindered by the lack of a standardized definition for mild HIE that will reliably identify at-risk infants who may benefit from neuroprotective strategies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Early Human Development - Volume 120, May 2018, Pages 88-94
نویسندگان
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