کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8779166 1600020 2017 23 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Urothelial Bladder Cancer: An Update on Molecular Pathology with Clinical Implications
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Urothelial Bladder Cancer: An Update on Molecular Pathology with Clinical Implications
چکیده انگلیسی
Urothelial bladder cancer is a heterogenous disease with distinct clinical and histopathological features. In the last few years it became clear that papillary, mostly noninvasive, disease with few molecular changes and aggressive urothelial carcinoma are genomically separate diseases. Recently, several studies found that invasive bladder cancer can also be separated into several molecular subgroups. In the present review we summarize molecular alterations, diagnostic markers, and molecular subgroups in urothelial bladder cancer and discuss their clinical relevance for prognosis, prediction of recurrence and progression, and therapeutic response to chemotherapy, radiotherapy, and immunotherapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Urology Supplements - Volume 16, Issue 12, December 2017, Pages 272-294
نویسندگان
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