Radiological and histological findings characteristic of AIDS related Burkitt lymphoma

ObjectiveTo explore the radiological and histological findings characteristic of AIDS related Burkitt lymphoma.MethodsRadiological and histological data from 4 patients with AIDS related Burkitt lymphoma were retrospectively analyzed. All the 4 patients received CT scanning and MR imaging. Of the 4 patients, 3 underwent surgical removal of lymphoma and the other 1 was performed aspiration biopsy.ResultsAll the 4 patients were detected with superficial lymphadenopathy, with 2 at the neck and the other 2 at the armpit. Extra-nodal invasion were found in 3 patients, of which 2 had multi-organ lesions. Their diagnoses were histologically defined to be Burkitt lymphoma.ConclusionAIDS-related Burkitt lymphoma is radiologically shown as lymphadenopathy and multi-organ involvement. Diffuse tumor cells with moderate sizes exist in intra- and extra-nodal tissues, characterized by stars-in-the-sky sign. Immunohistochemically, both CD10 and CD20 are positive, and the positive rate of Ki67 is almost up to 100%.