Stargardt Macular Dystrophy

Despite having eccentric fixation, most STGD participants did not have a complete directional re-referencing from the fovea to the eccentric location, and moved fixation when asked to look straight ahead. This finding emphasizes that reliable assessment of visual function during evaluations of disease progression or in therapeutic intervention trials requires consistent instructions and monitoring of fixation. Otherwise, a patient's interpretation of fixation instruction may confound the results.