Secondary glioblastoma with abdominal metastasis: Case report

Extracranial glioblastoma (GB) metastasis is an uncommon entity, rarely described in the literature, representing 0.2% of cases of GB. Several theories have been proposed to explain the extracranial dissemination of GB, such as surgical interventions, ventriculoperitoneal shunt, and radiation therapy. We present a case of a 15-year old adolescent girl, with an initial diagnosis of low-grade glioma and later transformation to a high-grade glioma. In the final phase of the disease, the patient presented with distention and abdominal pain, secondary to peritoneal compromise of GB metastasis. The use of new therapies has increased survival times, leading to a rise in the probability of developing extracranial metastasis.