کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8838815 1613216 2018 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Epigenetic regulation of Fgf1 transcription by CRTC1 and memory enhancement
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
Epigenetic regulation of Fgf1 transcription by CRTC1 and memory enhancement
چکیده انگلیسی
Recent evidence demonstrates that epigenetic regulation of gene transcription is critically involved in learning and memory. Here, we discuss the role of histone acetylation and DNA methylation, which are two best understood epigenetic processes in memory processes. More specifically, we focus on learning-strength-dependent changes in chromatin on the fibroblast growth factor 1 (Fgf1) gene and on the molecular events that modulate regulation of Fgf1 transcription, required for memory enhancement, with the specific focus on CREB-regulated transcription coactivator 1 (CRTC1).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research Bulletin - Volume 141, July 2018, Pages 3-12
نویسندگان
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