کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8840023 | 1614496 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Cortical dendritic spine development and plasticity: insights from in vivo imaging
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Cortical dendritic spine development and plasticity: insights from in vivo imaging Cortical dendritic spine development and plasticity: insights from in vivo imaging](/preview/png/8840023.png)
چکیده انگلیسی
Dendritic spines are the postsynaptic sites of most excitatory synapses in the cerebral cortex. Their morphology and density change throughout life, reflecting the maturation and reorganization of excitatory circuits. The development of in vivo two-photon microscopy has enabled the monitoring of the same dendritic spines over time during different developmental periods. In this review we focus on recent in vivo imaging studies in rodents that have revealed cell type-specific and region-specific structural dynamics of dendritic spines. We also discuss how the contributions of local inhibitory neurons and long-distance excitatory and neuromodulatory inputs to the cortex influence dendritic spine development and dynamics. Such studies will facilitate our understanding of how environmental factors and experiences affect cortical synapse development.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Neurobiology - Volume 53, December 2018, Pages 76-82
Journal: Current Opinion in Neurobiology - Volume 53, December 2018, Pages 76-82
نویسندگان
Caitlin E Moyer, Yi Zuo,