کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8840956 | 1614703 | 2018 | 43 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
EEG Dynamics and Neural Generators in Implicit Navigational Image Processing in Adults with ADHD
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کلمات کلیدی
ERSERPsERDERSPEEG dynamicsPOZattention-deficit hyperactivity disorder - اختلال بیش فعالی کمبود توجهevent-related spectral perturbation - اختلال طیفی مربوط به رویدادADHD - بیشفعالیevent-related desynchronization - ناسازگاری مربوط به رویدادevent-related synchronization - همزمان سازی مرتبط با رویدادOddball paradigm - پارادایم عجیب و غریبEvent-related potentials - پتانسیل مربوط به رویداد یا ERP Control - کنترل
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In contrast to childhood ADHD that is characterized by inattention, impulsivity and hyperactivity, most adults with ADHD predominantly exhibit inattention. We used a new oddball paradigm using implicit navigational images and analyzed EEG dynamics with swLORETA inverse modeling of the evoked potential generators to study cortical processing in adults with ADHD and age-matched controls. In passive observation, we demonstrated that P350 amplitude, alpha-beta oscillation event-related synchronization (ERS) anticipation, and beta event-related desynchronization (ERD) were significantly smaller in ADHD. In the active condition, P100 duration was reduced and N140 amplitude increased for both deviant and frequent conditions in the ADHD. Alpha ERS and delta-theta ERS were reduced in the ADHD in the deviant condition. The left somatosensory area (BA2) and the right parietal lobe (BA31, BA40) contributed more to the P100 generators in the control than in the ADHD group, while the left frontal lobe (BA10) contributed more to the P100 generators in the ADHD. The left inferior parietal lobe (BA40) contributed more to the N140 generators in the control than the ADHD group while the right posterior cingulate (BA30) contributed more to the N140 generators in the ADHD. These findings reinforce the notion that earlier cortical stages of visual processing are compromised in adult ADHD by inducing the emergence of different even-related potential generators and EEG dynamics in ADHD. Considering that classical approaches for ADHD diagnosis are based on qualitative clinical investigation possibly biased by subjectivity, EEG analysis is another objective tool that might contribute to diagnosis, future neurofeedback or brain stimulation therapies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 373, 1 March 2018, Pages 92-105
Journal: Neuroscience - Volume 373, 1 March 2018, Pages 92-105
نویسندگان
A. Leroy, G. Petit, D. Zarka, A.M. Cebolla, E. Palmero-Soler, J. Strul, B. Dan, P. Verbanck, G. Cheron,