کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8876244 | 1623717 | 2016 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effect of Atipamzole on Fos Protein Expression Induced by Telazol/Xylazine in Rat Cerebral Cortex and Thalamencephal
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
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چکیده انگلیسی
The aim of the study was to assess effect of the atipamezole on talezol/xylazine induced expression of c-fos in rat brain. Rats were injected with the mixture of 13.81 mg · kgâ1 telazol and 5.21 mg · kgâ1 xylazine, following 10 min later 0.522 mg · kgâ1 atipamezole injected, and then the cerebral cortex and thalamencephal were removed at 1 h after injected. Level of Fos protein was measured in the brain tissue by western-blot. The results revealed that telazol/xylazine induction Fos protein expression in the thalamencephal and cerebral cortex during the period of anesthesia, atipamezole attenuated telazol/xylazine induction Fos protein expression in the thalamencephal and cerebral cortex. The results indicated that atipamezole could inhibite telazol/xylazine-induced c-fos expression in the rat brain, and played a protective role of neuronal injury.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Northeast Agricultural University (English Edition) - Volume 23, Issue 4, December 2016, Pages 61-66
Journal: Journal of Northeast Agricultural University (English Edition) - Volume 23, Issue 4, December 2016, Pages 61-66
نویسندگان
Yin Bai-shuang, Gao Li, Fu Lian-jun, Hong-jin LI, Wang Hong-bin,