Identification of the active portion of the CCL3 derivative reported to induce antitumor abscopal effect

Q/C peptide maps to the eMIP β-sheet: 3 adjacent anti-parallel strands connected by the β-hairpins, is the active portion of eMIP necessary for an immunomodulatory antitumor effect. This experimental reduction furthers our understanding of the underlying mechanism of the abscopal effect. The data will open the way for therapeutic application of like peptides.