ICG@ZIF-8: One-step encapsulation of indocyanine green in ZIF-8 and use as a therapeutic nanoplatform

This work reports a one-step encapsulation of Indocyanine Green (ICG) in ZIF-8 nanoparticles (NPs), which possess an absorption band in the near infrared region and have the good photothermal conversion efficiency. The in vivo and in vitro studies show that, after loading DOX, ICG@ZIF-8-DOX NPs exhibit the chem-and photothermal synergistic therapy for tumor.