کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9005734 1120066 2005 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Practical approaches to insulin therapy for type 2 diabetes mellitus with premixed insulin analogues
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Practical approaches to insulin therapy for type 2 diabetes mellitus with premixed insulin analogues
چکیده انگلیسی
Premixed insulin analogues have a more physiologic time-action profile, can be administered closer to mealtime, and produce greater reductions in the magnitude of postprandial glucose excursions than human insulin 70/30. Despite these advantages, no consistent differences in HbA1c reduction or the incidence of hypoglycemia versus human insulin 70/30 have been found in most short-term trials. Although there is an increased risk of minor hypoglycemia, patients using premixed insulin analogues twice daily are more likely to reach HbA1c goals than those using only insulin glargine once daily. Further studies are necessary to examine whether these advantages improve patient outcomes in clinical practice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Therapeutics - Volume 27, Issue 8, August 2005, Pages 1113-1125
نویسندگان
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