کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9006953 | 1559666 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Anti-nociceptive activity of the aqueous extract of Erythrina velutina leaves
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Anti-nociceptive activity of the aqueous extract of Erythrina velutina leaves Anti-nociceptive activity of the aqueous extract of Erythrina velutina leaves](/preview/png/9006953.png)
چکیده انگلیسی
Anti-nociceptive and anti-oedematogenic effects of the aqueous extract from the leaves of Erythrina velutina were tested through experimental models of nociception in mice and paw oedema induced by carrageenin in rats. The extract (300 and 600 mg/kg) did not change the carrageenin-induced paw oedema. In the hot plate test the extract also did not alter the latency time for mice liking the rear paws. Moreover, the extract (600 mg/kg) decreased by 96.5% the paw liking time in the second phase of the formalin test. This effect was antagonized by naloxone (5 mg/kg). In the acetic acid-induced writhing test, the extract (300 and 600 mg/kg) reduced the number of writhing by 88.8% and 96.4%, respectively. Our present results demonstrated that the crude extract from the leaves of E. velutina has anti-nociceptive but not anti-oedematogenic properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 76, Issues 7â8, December 2005, Pages 637-642
Journal: Fitoterapia - Volume 76, Issues 7â8, December 2005, Pages 637-642
نویسندگان
Murilo Marchioro, Maria de Fátima Arrigoni Blank, Rosa Helena Veras Mourão, Ãngelo Roberto Antoniolli,