کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9007000 | 1122205 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antifilarial activity of Azadirachta indica on cattle filarial parasite Setaria cervi
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Alcohol and aqueous extracts of flowers of Azadirachta indica were tested in vitro for their potential antifilarial activity against whole worm, nerve muscle (n.m.) preparation and microfilariae of Setaria cervi. The effects of alcohol and aqueous extracts were similar in nature on the spontaneous movements of whole worm and nerve muscle preparation. On the whole worm, the response was characterized by initial increase in tone, rate and amplitude of contractions followed by reversible paralysis. The initial stimulant effect is likely to be due to irritant effect on the cuticle. Nerve muscle preparation responded to both extracts by inhibition of spontaneous movements followed by reversible paralysis; initial stimulation phase was absent. The inhibition was concentration related. Alcohol and aqueous extracts had almost similar lethal effect on the microfilariae of S. cervi, the LC50 being 15 and 18 ng/ml, respectively.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 76, Issue 1, January 2005, Pages 54-61
Journal: Fitoterapia - Volume 76, Issue 1, January 2005, Pages 54-61
نویسندگان
Vandna Mishra, Nazneen Parveen, K.C. Singhal, Nizam U. Khan,