کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9021404 | 1561373 | 2005 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Update on improving the bio-implant interface by controlling cell behaviour using surface topography
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی مولکولی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
The topography of surfaces contacting cells profoundly influences their behaviour. Precisely controlled topographies can be produced by microfabrication methods and uniform surface chemistry can be obtained by coating methods. Topographic effects on some key processes in implant integration are reviewed including cell orientation, cell shape, cytoskeletion, migration, in vivo and in vitro behaviour, and tissue organization by cytomechanical action. Macrophages' reactions to topography provide new insights into the success of rough implant surfaces. The potential of microfabricated structures to control cell behaviour has barely been tapped and there are many opportunities for using substratum topographic control of cell behaviour in applications ranging from implanted devices to cell culture production services.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Congress Series - Volume 1284, September 2005, Pages 229-238
Journal: International Congress Series - Volume 1284, September 2005, Pages 229-238
نویسندگان
D.M. Brunette, D.W. Hamilton, B. Chehroudi, J.D. Waterfield,