کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9051447 | 1136591 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Histamine at high dilution reduces spectral density in delta band in sleeping rats
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب مکمل و جایگزین
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چکیده انگلیسی
Histamine is a central neurotransmitter, it increases arousal via H1 receptors. This study examines the effect of ultra-diluted histamine on arousal through changes in the sleep pattern of Wistar rats. The spectral density in delta (0.5-2.5Â Hz) band, one of the three major spectral components of the sleep-electroencephalogram, was analyzed against time. Rats were randomized to receive histamine 30c (histamine 30c, 0.05Â ml every 20Â min during the first 2Â h orally), histamine intraperitoneal pre-treatment/histamine 30c (histamine 6Â mg/kg i.p., followed by histamine 30c) or solvent control. The mean delta band spectral density was lower in the histamine 30c and histamine pretreatment/histamine 30c groups than the control group. Significant differences between histamine 30c and baseline during the first 2Â h imply an immediate effect. These results also suggest a dynamic process in which the system spontaneously evolves between two locally stationary states according to a power law. From the time perspective, the system approaches, asymptotically, an equifinal state.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Homeopathy - Volume 94, Issue 2, April 2005, Pages 86-91
Journal: Homeopathy - Volume 94, Issue 2, April 2005, Pages 86-91
نویسندگان
G Ruiz-Vega, B Poitevin, L Pérez-Ordaz,