کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9059584 | 1139844 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Soy Isoflavone and Ascorbic Acid Supplementation Alone or in Combination Minimally Affect Plasma Lipid Peroxides in Healthy Postmenopausal Women
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش تغذیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The objective of this study was to assess synergistic antioxidant properties of vitamin C and isoflavones. The design was a placebo-controlled crossover trial: 500 mg vitamin C, 5 mg/kg body weight isoflavones, 500 mg vitamin C plus 5 mg/kg body weight isoflavones, or placebo. Total lipid peroxides, plasma vitamin C, and blood pressure were measured. Eight of 10 healthy postmenopausal women completed the study. A multiple analysis of variance was performed and least-squares difference post-hoc test utilized to determine where differences occurred. Significance was defined as P<.05. There was a significant reduction in total lipid peroxides between baseline and isoflavone treatments (3.22±0.72 vs 2.47±0.82 nmol/mL, P<.05). Mean systolic blood pressure was higher during isoflavone intervention than placebo (117±14 vs 125±15 mm Hg, P=.042). Supplementation with vitamin C and isoflavones did not produce a synergistic antioxidant effect. A slight but significant increase in systolic blood pressure occurred with isoflavone supplementation. A larger study should be conducted to fully explore the potential interactions between these antioxidants.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Dietetic Association - Volume 105, Issue 7, July 2005, Pages 1134-1137
Journal: Journal of the American Dietetic Association - Volume 105, Issue 7, July 2005, Pages 1134-1137
نویسندگان
Andrea M. PhD, RD, Imogene E. MS, RD, Carol S. PhD, RD,