کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9076951 | 1144714 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Systemic Risk Factors Associated with Progression of Atherosclerosis from the Coronary to the Carotid Arteries
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
مغز و اعصاب بالینی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Systemic Risk Factors Associated with Progression of Atherosclerosis from the Coronary to the Carotid Arteries Systemic Risk Factors Associated with Progression of Atherosclerosis from the Coronary to the Carotid Arteries](/preview/png/9076951.png)
چکیده انگلیسی
Background: It is unclear why atherosclerosis remains restricted to one arterial tree in some patients whereas it is more generalized in others. Few studies have addressed the role that systemic risk factors play in the progression of atherosclerosis from one arterial tree to another. Methods: We studied 344 consecutive patients with suggested coronary artery disease (CAD) who underwent combined coronary and carotid angiography during a 7-month period. Coronary and carotid disease was graded as absent-mild or moderate-severe based on the degree of stenosis of these vessels. Traditional vascular risk factors were compared for patients with moderate-severe CAD alone versus patients with moderate-severe CAD and carotid disease. Results: Moderate-severe CAD alone was found in 162 patients and moderate-severe CAD and carotid disease was found in 100 patients. Multivariate analysis showed that hypertension (P = .007, odds ratio 2.2, 95% confidence interval 1.2-3.9), history of smoking (P = .06, odds ratio 1.8, 95% confidence interval 1.0-3.4), and diabetes (P = .09, odds ratio 1.6, 95% confidence interval 0.9-2.8) were associated with combined moderate-severe CAD and carotid disease. Patients with combined moderate-severe CAD and carotid disease were significantly more likely to have at least 2 of these 3 risk factors (P < .001) than patients with moderate-severe CAD alone. Conclusion: An accumulating burden of hypertension, diabetes, and smoking are important in the progression of atherosclerosis from the coronary to the carotid circulation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Stroke and Cerebrovascular Diseases - Volume 14, Issue 4, JulyâAugust 2005, Pages 182-185
Journal: Journal of Stroke and Cerebrovascular Diseases - Volume 14, Issue 4, JulyâAugust 2005, Pages 182-185
نویسندگان
As'ad MD, Marc I. MB, ChB, Anthony J. MD, E. Frank MD,