کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9142062 1163895 2005 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Peripheral NK cell phenotypes: multiple changing of faces of an adapting, developing cell
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی مولکولی
پیش نمایش صفحه اول مقاله
Peripheral NK cell phenotypes: multiple changing of faces of an adapting, developing cell
چکیده انگلیسی
We have defined the existence of developmental relationships among human peripheral NK cells with distinct phenotypic and functional characteristics. These findings closely parallel the changes that occur in vivo during NK cell development, and in vitro in experimental culture systems supporting NK cell generation from hematopoietic progenitors. These new insights provide a simplified framework to understand NK cell immunobiology and the cellular bases for their roles in innate immunity, initiation and maintenance of immune responses via regulation of adaptive and accessory cell functions, and immune pathologies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Molecular Immunology - Volume 42, Issue 4, February 2005, Pages 385-395
نویسندگان
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