Cholecystokinin1 receptors mediate the increase in Fos-like immunoreactivity in the rat myenteric plexus following intestinal oleate infusion

These data confirm previous reports indicating that CCK1 receptors mediate increased DVC Fos-LI following intestinal infusion of oleate or glucose. CCK1 receptors also contribute to increased Fos-LI in enteric neurons following intestinal oleate infusion. However, failure of lorglumide to attenuate the increase of Fos-LI in the ileal submucosal plexus following intestinal glucose suggests that some intestinal nutrients trigger Fos-LI induction via CCK1 receptor-independent pathways.