کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9152182 | 1571357 | 2005 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Assessment of lung microstructure with magnetic resonance imaging of hyperpolarized Helium-3
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
فیزیولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Assessment of lung microstructure with magnetic resonance imaging of hyperpolarized Helium-3 Assessment of lung microstructure with magnetic resonance imaging of hyperpolarized Helium-3](/preview/png/9152182.png)
چکیده انگلیسی
Magnetic resonance imaging of the apparent diffusion coefficient (ADC) of hyperpolarized Helium-3 is a new technique for probing pulmonary microstructure in vivo. The aim of this study was the assessment of potential sources of systematic errors of the ADC measurement. The influence of macroscopic motion was determined by measurements at two different delays after initiating the breath-hold, and before and after cardiac arrest. An intercentre comparison was performed in two age- and lung function-matched groups of lung-healthy volunteers at two research sites. Moreover, measurements of diffusion anisotropy were performed. We found no dependency of the ADC as a function of the delay after stop of inspiration. The influence of cardiac motion was less than 10%. In the intercentre comparison study, an excellent agreement between the two sites was found. First measurements of the diffusion tensor of intrapulmonary Helium-3 are shown.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Physiology & Neurobiology - Volume 148, Issues 1â2, 25 August 2005, Pages 23-42
Journal: Respiratory Physiology & Neurobiology - Volume 148, Issues 1â2, 25 August 2005, Pages 23-42
نویسندگان
Wolfgang G. Schreiber, Andreas E. Morbach, Trine Stavngaard, Klaus K. Gast, Anette Herweling, Lise Vejby Søgaard, Michael Windirsch, Jörg Schmiedeskamp, Claus Peter Heussel, Hans-Ulrich Kauczor,