Nitric Oxide Is Released Into Circulation With Whole-Body, Periodic Acceleration*

Whole-body, periodic acceleration increased pulsatile shear stress to the endothelium leading to vasodilatation and a fall in the dicrotic notch, consistent with increased NO bioactivity in every healthy adult and adult patient with inflammatory disease so treated. Therefore, passive exercise using whole-body, periodic acceleration produces an important benefit that occurs with active exercise.