کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9187341 | 1184483 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Autonomic dysfunction in cases of spinal muscular atrophy type 1 with long survival
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Autonomic dysfunction in cases of spinal muscular atrophy type 1 with long survival Autonomic dysfunction in cases of spinal muscular atrophy type 1 with long survival](/preview/png/9187341.png)
چکیده انگلیسی
In Japan, quite a few patients with spinal muscular atrophy type 1 (SMA type 1) survive with mechanical ventilation. Since a patient with SMA type 1 and continuous artificial ventilation exhibited excessive perspiration and tachycardia, we examined the autonomic functions in three cases of SMA type 1, undergoing mechanical ventilation. Two cases exhibited the common sympathetic-vagal imbalance on R-R interval analysis involving 24-h Holter ECG recordings in addition to an abnormality in finger cold-induced vasodilatation. Furthermore, one case showed blood pressure and heart rate fluctuation with the paroxysmal elevation, and a high plasma concentration of norepinephrine during tachycardia. These findings suggest that autonomic dysfunction should be examined in SMA type 1 patients with long survival, although the pathogenesis remains to be clarified.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Development - Volume 27, Issue 8, December 2005, Pages 574-578
Journal: Brain and Development - Volume 27, Issue 8, December 2005, Pages 574-578
نویسندگان
Yasuo Hachiya, Hidee Arai, Masaharu Hayashi, Satoko Kumada, Wakana Furushima, Eiko Ohtsuka, Yasushi Ito, Akira Uchiyama, Kiyoko Kurata,