کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
920060 920262 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Response preparation in Parkinson's disease: Automatic vs. controlled processing
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
Response preparation in Parkinson's disease: Automatic vs. controlled processing
چکیده انگلیسی

Using a finger cuing paradigm, we investigated response preparation in Parkinson's disease (PD). The central question was whether PD individuals are differentially affected by preparatory cues that specify a more automatic response set configuration (that induces within-hand preparation) as opposed to a more controlled one (that induces between-hands preparation). Reaction times (RTs) and error rates were measured in 20 non-demented individuals with PD and 20 healthy control participants with a long and short preparation interval (500 ms and 2000 ms). RT benefits and/or costs were measured for cues indicating a within- and between-hands motor preparatory set. Overall, RTs were significantly longer, and errors more frequent, for PD participants than for control participants. More importantly, in comparison with control subjects, PD individuals showed a significant deficit in between-hands preparation but not in within-hand preparation. Furthermore, longer preparation intervals slowed down cued RTs of the control participants, but not those of the PD individuals. Together, these findings suggest that whereas automatic response preparation processes are spared in PD, controlled response preparation processes operate at a slower rate and/or are delayed in time.


► We examined response preparation in Parkinson Disease (PD).
► Within-hand response preparation is spared in PD.
► Between-hands response preparation is affected in PD.
► Cued reaction times of PD subjects are not affected by longer preparation intervals.
► Cued reaction times of control subjects slow down with longer preparation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Psychologica - Volume 139, Issue 3, March 2012, Pages 465–470
نویسندگان
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