کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9200687 | 1189406 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Diaphragmatic dysfunction in patients with idiopathic inflammatory myopathies
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب تکاملی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Polymyositis, dermatopolymyositis, and inclusion body myositis imply chronic inflammation of skeletal muscles. Pulmonary complications include aspiration pneumonia, interstitial pneumonitis, or respiratory muscle myositis. This study aims at better describing their impact on respiratory muscle. Twenty-three consecutive patients (12 PM, 5 DM, 6 IBM) were studied (static inspiratory and expiratory pressures; diaphragm function in terms of the mouth and transdiaphragmatic pressure responses to bilateral phrenic stimulation). Pulmonary parenchymatous abnormalities were mild (6 cases) or absent. The mouth pressure produced by phrenic stimulation was 6.83±3.01 cmH2O, with 18 patients (78%) diagnosed with diaphragm weakness (<10 cmH2O) and lower values in DM (4.35±1.48 cmH2O) than in IBM and in PM (P<0.05). Diaphragm weakness is frequent and probably overlooked in inflammatory myopathies. Further studies are needed to delineate the clinical relevance of these results.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuromuscular Disorders - Volume 15, Issue 1, January 2005, Pages 32-39
Journal: Neuromuscular Disorders - Volume 15, Issue 1, January 2005, Pages 32-39
نویسندگان
Antonio Teixeira, Patrick Cherin, Alexandre Demoule, Michèle Levy-Soussan, Christian Straus, Eric Verin, Marc Zelter, Jean-Philippe Derenne, Serge Herson, Thomas Similowski,