کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
920874 1473868 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mismatch negativity indices of enhanced preattentive automatic processing in panic disorder as measured by a multi-feature paradigm
ترجمه فارسی عنوان
شاخص های منفی ناتوانی در پردازش خودکار پیشگیرانه افزایش یافته در اختلال هراس از طریق پارادایم چند ویژگی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


• Preattentive automatic information processing of PD patients was measured by MMN.
• PD patients showed a significantly increased MMN of sound intensity and location.
• Anomalous preattentive automatic information processing was found in PD patients.
• Our findings provide new evidence for three-stage model of anxiety disorders.

Panic disorder (PD) is a mental disorder characterized by recurrent panic attacks and worrying about having subsequent attacks. Mismatch negativity (MMN) has been established as a correlate of preattentive automatic processing. The aim of the present study is to investigate the preattentive automatic information processing in PD patients as measured by MMN. Subjects included 15 medication-free patients with a DSM-IV diagnosis of PD and 15 age-matched healthy volunteers. MMN was investigated using event-related potentials. The protocol used a multi-feature paradigm. Mean amplitudes and peak latencies were subjected to repeated-measures ANOVAs. PD patients showed a significantly increased MMN of sound intensity and location compared with healthy participants. The correlation between the amplitudes of intensity-MMN and disease severity was also significant. These data provide evidence of anomalous preattentive automatic information processing in PD patients. In particular, the abnormality may be specific for PD.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biological Psychology - Volume 105, February 2015, Pages 77–82
نویسندگان
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