کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
921542 920783 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Do the same genetic and environmental effects underlie the covariation of alcohol dependence, smoking, and aggressive behaviour?
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Do the same genetic and environmental effects underlie the covariation of alcohol dependence, smoking, and aggressive behaviour?
چکیده انگلیسی

We investigated genetic and environmental effects on alcohol dependence, smoking, and aggressive behaviour, as well as sex differences in these effects and whether these effects were the same for the three phenotypes. There were 3141 male (mean age 26.2 [S.E. = 0.1]) and 6026 female (mean age 26.1 [S.E. = 0.1]) participants in this extended twin study. Alcohol Use Disorder Identification Test (AUDIT), number of cigarettes smoked, and two subscales of Aggression Questionnaire (AQ) were used to assess the phenotypes. All three were positively interrelated with males exhibiting higher levels on each phenotype. Multivariate model fitting identified genetic effects on all phenotypes for both men and women ranging between 69% (aggressive behaviour in women) and 78% (alcohol dependence in men). The effects were stronger in men for alcohol dependence and smoking. There were no qualitative genetic sex differences. Genetic correlations between all phenotypes were substantial.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biological Psychology - Volume 78, Issue 3, July 2008, Pages 269–277
نویسندگان
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