کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9298315 1244924 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Trombofilia congénita y aborto recurrente: estrategias diagnósticas y recomendaciones terapéuticas
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Trombofilia congénita y aborto recurrente: estrategias diagnósticas y recomendaciones terapéuticas
چکیده انگلیسی
Pregnancy is a well recognized thrombophilic risk factor. Recurrent abortion (RA) affect up to 3% of fertile couples. A 50% of these cases are considered as idiopathic. Some of them may have one or more than one thrombophilic alterations. RA may be related to placental flow abnormalities. Up to 1% to 5% of all pregnancies may be complicated with placental flow abnormalities. Antiphospholipid syndrome, PS, PC, ATIII deficiencies, factor V, prothrombine, methilentetrahidrofolate reductase, plasminogen activador inhibidor type 1, fibrinogen and factor XIII polymorphisms, have been strongly related to bad obstetric outcomes, specially RA. The presence of more than one thrombophilic factor may be present in pregnant women, rising the risk of suffering RA. All pregnant patients and those who planed a future conception having a history of thrombotic events, independently of their previous obstetric outcomes, need to be studied for thrombophilia. All patients with RA specially if it appeared in the latepregnancy, have also to be studied. Early antiagreggant and/or anticoagulant therapy, reduces the maternal-fetal risk.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medicina Clínica - Volume 125, Issue 16, November 2005, Pages 626-631
نویسندگان
, ,