کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9311408 1250263 2005 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Uric acid and preeclampsia
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Uric acid and preeclampsia
چکیده انگلیسی
Increased uric acid level is a key clinical feature of preeclampsia; higher levels correlate with significant maternal and fetal morbidity and mortality. The cause of hyperuricemia and its specific role in the pathogenesis of preeclampsia, however, remain unclear. Although uric acid has been shown to roughly parallel the severity of the maternal syndrome, it has not been useful in predicting the development of preeclampsia. Nevertheless, there have been recent data supporting a pathogenic role potentially in the hypertension and endothelial cell dysfunction of preeclampsia. This article reviews our current understanding of hyperuricemia in the setting of preeclampsia, and highlights the hypothesis that hyperuricemia may contribute to vascular damage in preeclampsia.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Nephrology - Volume 25, Issue 1, January 2005, Pages 56-60
نویسندگان
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