Avortements spontanés à répétition

Recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses at less than 24 weeks of gestation; this condition affects 1% of fertile couples. RM is a clinical condition of heterogeneous aetiology; however, in 50% of the cases no cause is identified. Classification of RM is a crucial tool in the investigation, exploration and treatment of pathophysiological mechanisms. Uterine defects, chromosome and genetic abnormalities, hormonal and metabolic disorders, infectious causes, acquired and inherited thrombophilia, immunologic disorders, male and environmental factors are the principal causes of RM.