Tamsulosin Oral Controlled Absorption System (OCAS) in Patients with Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia (LUTS/BPH): Efficacy and Tolerability in a Phase 2b Dose-Response Study

All three tamsulosin OCAS doses tested were effective in relieving urinary symptoms and improving disease-specific quality of life in LUTS/BPH patients. The 0.8 mg and, in particular, the 0.4 mg doses were better tolerated than the 1.2 mg dose. Therefore, these two doses were selected for further evaluation in a phase 3a placebo- and comparator (tamsulosin modified release capsules) controlled trial.