کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9348527 1263584 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Measuring the cone contribution to the ERG b-wave to assess function and predict anatomical rescue in RCS rats
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
پیش نمایش صفحه اول مقاله
Measuring the cone contribution to the ERG b-wave to assess function and predict anatomical rescue in RCS rats
چکیده انگلیسی
Subretinal injections of human retinal pigment epithelial (RPE) cells early in the course of retinal degeneration in Royal College of Surgeons (RCS) rats can rescue photoreceptors. Fourteen injected animals were studied using a double flash electroretinogram (ERG): 10 were examined longitudinally and four terminally with immunohistochemistry. The proportion of cone contribution to the ERG b-wave rather than the absolute size of isolated cone response proved to be a reliable indicator of function over time and a predictor of the proportion of cones identified anatomically in the area of optimal photoreceptor rescue.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vision Research - Volume 45, Issue 5, March 2005, Pages 635-641
نویسندگان
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