کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
940388 | 924889 | 2012 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Lactate infusion during euglycemia but not hypoglycemia reduces subsequent food intake in healthy men
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش تغذیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Considering that lactate is known to interact with central glucose-sensing networks, we tested whether hyperlactatemia affects food intake in humans. According to a balanced within-subject 2 × 2 design, 12 healthy, fasted men (age: 20–40 years; BMI: 20–26 kg/m2) were intravenously infused lactate and saline, respectively, for 105 min during concomitant euglycemic and hypoglycemic, respectively, insulin infusion of 75 min. Ten minutes after the simultaneous end of infusions, free-choice food intake was assessed at 10:25 h. Lactate decreased food intake following euglycemia as compared to the other three conditions in which food intake did not differ. Results point to an anorexigenic effect of lactate under euglycemic conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Appetite - Volume 58, Issue 3, June 2012, Pages 818–821
Journal: Appetite - Volume 58, Issue 3, June 2012, Pages 818–821
نویسندگان
Bernd Schultes, Sebastian M. Schmid, Britta Wilms, Kamila Jauch-Chara, Kerstin M. Oltmanns, Manfred Hallschmid,