کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9406346 | 1290112 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Progestin-facilitated lordosis of hamsters may involve dopamine-like type 1 receptors in the ventral tegmental area
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Progestin-facilitated lordosis of hamsters may involve dopamine-like type 1 receptors in the ventral tegmental area Progestin-facilitated lordosis of hamsters may involve dopamine-like type 1 receptors in the ventral tegmental area](/preview/png/9406346.png)
چکیده انگلیسی
Hamsters are highly-dependent upon the central actions of progesterone (P) to facilitate sexual behavior. P has membrane mechanisms of action in the ventral tegmental area (VTA) to facilitate sexual receptivity of rodents. The present experiments examined whether P's membrane actions in the VTA include dopamine (DA) type 1 (D1) or dopamine type 2 (D2) receptors. Ovariectomized (ovx), estradiol (E2)- and P-primed hamsters were infused with D1 (Experiment 1) or D2 (Experiment 2) antagonists or agonists (0 or 100Â ng) to the VTA and tested 30Â min later. The D1 agonist, SKF38393, enhanced P-facilitated lordosis. The D1 antagonist, SCH23390, attenuated P-facilitated lordosis. The D2 agonist, quinpirole and the D2 antagonist, sulpiride, had no significant effects on P-facilitated lordosis. These data suggest that, in hamsters, P's actions for lordosis may involve D1 receptors in the VTA.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Behavioural Brain Research - Volume 161, Issue 1, 3 June 2005, Pages 1-7
Journal: Behavioural Brain Research - Volume 161, Issue 1, 3 June 2005, Pages 1-7
نویسندگان
Kanako Sumida, Alicia A. Walf, Cheryl A. Frye,