کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9406364 1290112 2005 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immobility in the swim test and observations of maternal behavior in lactating flinders sensitive line rats
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Immobility in the swim test and observations of maternal behavior in lactating flinders sensitive line rats
چکیده انگلیسی
In order to elucidate the relationship between maternal behavior and depression, the Flinders sensitive line (FSL) model of depression was studied and compared to Sprague-Dawley (SD) controls. Immobility in the swim test was measured, as an index for depressive-like behavior, and frequencies of maternal and non-maternal behaviors were recorded using short un-intrusive observations in the home cage. Lactating FSL rats displayed higher levels of immobility in the swim test compared to controls, indicating depressive-like behavior. In addition, compared to SD rats, FSL dams showed less frequent pup licking and non-nutritive contact with pups during the first and third weeks of lactation. In the third postpartum week, FSL dams showed less frequent nursing postures and more frequent self-directed behaviors. Thus, lactating FSL dams exhibit both depressed-like behavior and some abnormalities in maternal behavior.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Behavioural Brain Research - Volume 161, Issue 1, 3 June 2005, Pages 155-163
نویسندگان
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