کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9416129 | 1614330 | 2005 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fos responses to short-term adaptation of the horizontal vestibuloocular reflex before and after vestibular compensation in the Mongolian gerbil
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کلمات کلیدی
VOChemilabyrinthectomyOKRPRHFPNPurkinjeFtnMVElong-term depression - افسردگی طولانی مدتImmunolabeling - ایمن سازیVideo-oculography - تصویر برداریOptokinetic reflex - رفلکس Optokineticinferior olive - زیتون ناقصVestibular system - سیستم دهلیزیMotor systems and sensorimotor integration - سیستم های موتور و ادغام سنسور حرکتیprepositus hypoglossi - عصب زیر زبانی شهردارflocculus - فلوکوسوسLTD - محدودmedial vestibular nucleus - هسته داخلی وادی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Fos responses to short-term adaptation of the horizontal vestibuloocular reflex before and after vestibular compensation in the Mongolian gerbil Fos responses to short-term adaptation of the horizontal vestibuloocular reflex before and after vestibular compensation in the Mongolian gerbil](/preview/png/9416129.png)
چکیده انگلیسی
Fos expression in vestibular brainstem and cerebellar regions was evaluated during vestibular adaptation in the Mongolian gerbil. In addition, vestibular adaptation was evaluated in both normal and compensated animals, as vestibular compensation reorganizes the vestibular pathway constraining adaptive processes. Behaviorally, discordant optokinetic and vestibular input induced appropriate high and low gain in horizontal angular vestibuloocular reflex responses. In normal animals, low gain adaptation was more complete than high gain. However, in compensated animals, only low gain adaptation produced adaptive responses both toward and away from the lesion with appropriate gain shifts. High gain adaptation in compensated animals failed to result in gain adaptation for head movements toward the side of the lesion. Fos expression during acute vestibular adaptation in normal animals was found in the flocculus/paraflocculus, the dorsal cap of the inferior olive (IOK), and the prepositus hypoglossi (PrH). Floccular Fos labeling was increased under both high and low gain conditions. IOK and PrH labeling was increased and correlated during low gain conditions, but was reduced and uncorrelated during high gain conditions. The pattern of Fos labeling in compensated animals was asymmetric-favoring the ipsilesional flocculus and contralesional vestibular brainstem. Both compensated high and low gain adaptation groups displayed increased floccular and IOK Fos labeling, but only compensated high gain adaptation produced increased Fos labeling in the medial vestibular nucleus. The behavioral and Fos labeling results are consistent with visual-vestibular adaptation requiring direct vestibular input.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research - Volume 1050, Issues 1â2, 19 July 2005, Pages 79-93
Journal: Brain Research - Volume 1050, Issues 1â2, 19 July 2005, Pages 79-93
نویسندگان
Michael E. Shinder, Adrian A. Perachio, Galen D. Kaufman,