The Pre-Optic Anterior Hypothalamus (POAH) partially mediates the hypothermic response to hemorrhage in rats

The mean drop in Tc following hemorrhage was 2.16 °C (N = 5) with hypothalamic heating, 1.35 °C (N = 5) with cooling, and 1.44 °C (N = 5) following the sham perfusion control. Heating of the POAH significantly exacerbated the hemorrhagic hypothermic response. These data further suggest that the POAH is at least partially responsible for mediating hemorrhagic hypothermia.