کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9423093 | 1294770 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Calcium pumps in the central nervous system
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Two families of Ca2+ transport ATPases are involved in the maintenance of Ca2+ homeostasis in the nervous system, the plasma membrane Ca2+-ATPase that pumps Ca2+ to the extracellular medium and the intracellular sarco/endoplasmic reticulum Ca2+-ATPase that transports Ca2+ from the cytosol to the endoplasmic reticulum. Both types of calcium pumps show precise regulatory properties and they are localized in specific subcellular regions. In this review, we describe the functional and regulatory properties of both families of calcium pumps, their distribution in nerve cells, and their involvement in neurological disorders. The functional characterization of neuronal calcium pumps is very important in order to understand the biochemical processes involved in the maintenance of intracellular calcium in synaptic terminals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research Reviews - Volume 49, Issue 2, September 2005, Pages 398-405
Journal: Brain Research Reviews - Volume 49, Issue 2, September 2005, Pages 398-405
نویسندگان
Ana M. Mata, M. Rosario Sepúlveda,