کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9424261 | 1295256 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Avoiding spectral leakage in objective detection of auditory steady-state evoked responses in the inferior colliculus of rat using coherence
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Local field potentials (LFP) are bioelectric signals recorded from the brain that reflect neural activity in a high temporal resolution. Separating background activity from that evoked by specific somato-sensory input is a matter of great clinical relevance in neurology. The coherence function is a spectral coefficient that can be used as a detector of periodic responses in noisy environments. Auditory steady-state responses to amplitude-modulated tones generate periodic responses in neural networks that may be accessed by means of coherence between the stimulation signal and the LFP recorded from the auditory pathway. Such signal processing methodology was applied in this work to evaluate in vivo, anaesthetized Wistar rats, activation of neural networks due to single carrier sound stimulation frequencies, as well as to evaluate the effect of different modulating tones in the evoked responses. Our results show that an inappropriate choice of sound stimuli modulating frequencies can compromise coherence analysis, e.g. misleading conclusions due to mathematical artefact of signal processing. Two modulating frequency correction protocols were used: nearest integer and nearest prime number. The nearest prime number correction was successful in avoiding spectral leakage in the coherence analysis of steady-state auditory response, as predicted by Monte Carlo simulations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroscience Methods - Volume 144, Issue 2, 15 June 2005, Pages 249-255
Journal: Journal of Neuroscience Methods - Volume 144, Issue 2, 15 June 2005, Pages 249-255
نویسندگان
Leonardo Bonato Felix, José Elvano Moraes, Antonio Mauricio Ferreira Leite Miranda de Sá, Hani Camille Yehia, Márcio Flávio Dutra Moraes,