کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9469936 | 1319074 | 2005 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A three-layer continuous model of porous media to describe the first phase of skin irritation
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A three-layer continuous model of porous media to describe the first phase of skin irritation A three-layer continuous model of porous media to describe the first phase of skin irritation](/preview/png/9469936.png)
چکیده انگلیسی
Mechanical skin irritation induces vasodilation on the line of scratch and in the neighboring zone. In order to model the effect of an irritation on the microcirculation, the vascular network has been described using a three-layer model. The first and last layer, considered as horizontal two-dimensional porous media, describe irrigation and drainage of the system, respectively. The intermediate layer, described by means of a lumped parameter method, does not permit horizontal fluxes. Hierarchical fluxes are directed from the first to the second layer and then towards the drainage layer in order to take into account physiological flow direction. Irritation is modeled by changing compliance of vessels situated at the entrance of the micro-circulation. The model permits to investigate the influence of change in compliance on flow and pressure behavior at microscopic and macroscopic level.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Theoretical Biology - Volume 232, Issue 3, 7 February 2005, Pages 347-362
Journal: Journal of Theoretical Biology - Volume 232, Issue 3, 7 February 2005, Pages 347-362
نویسندگان
D. Bauer, R. Grebe, A. Ehrlacher,