کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9478327 | 1324794 | 2005 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The toxic effect of phthalate esters on immune responses of giant freshwater prawn (Macrobrachium rosenbergii) via oral treatment
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم آبزیان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The toxic effect of phthalate esters on immune responses of giant freshwater prawn (Macrobrachium rosenbergii) via oral treatment The toxic effect of phthalate esters on immune responses of giant freshwater prawn (Macrobrachium rosenbergii) via oral treatment](/preview/png/9478327.png)
چکیده انگلیسی
A previous in vitro study has indicated that four phthalate esters (PAEs) could damage hemocytes and decreases the cellular immunity of prawns [Sung, H.H., Kao, W.Y., Su, Y.J., 2003. Effects and toxicity of phthalate esters to hemocytes of giant freshwater prawn, Macrobranchium rosenbergii. Aquat. Toxicol. 64, 25-37]. The aim of this study was to investigate the in vivo effect of four PAEs, diethyl phthalate (DEP), dihexyl phthalate (DHP), dipropyl phthalate (DPrP) and diphenyl phthalate (DPP) on the defense system of the giant freshwater prawn, M. rosenbergii. PAE dissolved in corn oil was continuously fed to prawns for 8 days and five immune parameters (total hemocyte count, THC; ratio of granulocytes to hyalinocytes, G/H; intrahemocytic total phenoloxidase activity, POT; intracellular superoxide anion (O2â) production; transglutaminase (TGase) activity) were separately detected on days 1, 4 and 8. In addition, mortality was determined on days 4 and 8 after challenging the prawns with Lactobacillus garvieae. In comparison with untreated prawns, the results showed that DHP demonstrated the lowest toxicity in that it only influenced the PO activity and O2â production before 4 days after treatment and caused 6.6% mortality on day 8. DEP decreased G/H, POT and TGase activity on day 1 and reduced THC, G/H and POT and caused 16.6% mortality on day 4; however, on day 8, it increased O2â production and caused no mortality. In the DPrP-treated group, a reduction of all the immune reactions apart from TGase activity and 22.2% mortality were detected on day 4. As for the effect of DPP, results showed that it decreased all the immune parameters apart from THC on days 1 and 4, but caused no mortality on day 4; but on day 8, an increase of O2â production and 17.7% mortality were detected. These results indicated that the immune reactions of prawns were variable due to the different toxic effects of PAEs. In addition, it was found that, on day 8 after treatment, the three PAEs, DHP, DPrP and DPP increased O2â production and did not influence the other four reactions, but mortality was detected in these groups. These results suggest that other physiological responses may also be affected to increase the susceptibility of prawns to pathogens.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Aquatic Toxicology - Volume 74, Issue 2, 30 August 2005, Pages 160-171
Journal: Aquatic Toxicology - Volume 74, Issue 2, 30 August 2005, Pages 160-171
نویسندگان
Wen-Liang Chen, Hung-Hung Sung,