کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
949900 926794 2009 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cardiovascular activity and the antibody response to vaccination
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Cardiovascular activity and the antibody response to vaccination
چکیده انگلیسی

ObjectiveTo examine the relationship between cardiovascular activity in response to acute psychological stress and the antibody response to vaccination.MethodsFifty-seven healthy participants were vaccinated with the trivalent influenza vaccine and meningococcal A+C polysaccharides. Antibody levels were measured at baseline and 5-weeks post-vaccination. Cardiovascular activity was measured at rest, during, and following a mental arithmetic stress task in 54 participants.ResultsParticipants demonstrating a fourfold increase in antibody titre to the A/Panama and B/Shangdong influenza strains and to meningococcal A showed greater blood pressure reactions toward the end of the acute stress task. In addition, there was some evidence of delayed diastolic blood pressure recovery in those who were responders to A/Panama and B/Shangdong influenza strains.ConclusionThe present results suggest that heightened cardiovascular reactivity to stress and delayed recovery may not necessarily be detrimental to all aspects of health and may be associated with an enhanced immune response to antigen challenge.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Psychosomatic Research - Volume 67, Issue 1, July 2009, Pages 37–43
نویسندگان
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