کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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950108 | 926806 | 2009 | 5 صفحه PDF | دانلود رایگان |
ObjectiveWhile the relation between alcohol consumption and mortality has been well explored, little is known about the link between alcohol problems and mortality in general population-based studies, particularly among women. This was the objective of the present studyMethodsIn this prospective cohort study, 5333 non-abstaining individuals (2539 women) from the UK-wide Health and Lifestyle Survey (aged 42.9 years at study induction) completed the CAGE questionnaire of alcohol problems and participated in a medical examination in 1984/1985; they were then followed up for mortality experience until 2005.ResultsAlcohol problems at baseline were less common in women (2.4%) than in men (7.8%). A total of 21 years of follow-up gave rise to 1201 deaths. Elevated rates of mortality were evident in persons reporting symptoms of alcohol problems in comparison to those who did not. In gender-stratified analyses, alcohol problems were more strongly associated with mortality risk in women (age-adjusted hazards ratio: 2.25; 95% confidence interval: 1.22–4.12) than in men (1.49; 1.12–1.99), although this effect modification was not statistically significant (P value for interaction=0.125). Controlling for a range of covariates—including socioeconomic position, co-morbidity (somatic and psychiatric), and alcohol intake—had essentially no impact on these associations.ConclusionThe CAGE questionnaire may have some utility in routine health assessments in the general population.
Journal: Journal of Psychosomatic Research - Volume 66, Issue 4, April 2009, Pages 317–321