کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9653462 | 679194 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A synapse which can switch from inhibitory to excitatory and back
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
هوش مصنوعی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A synapse which can switch from inhibitory to excitatory and back A synapse which can switch from inhibitory to excitatory and back](/preview/png/9653462.png)
چکیده انگلیسی
Co-release of transmitters has recently been observed at synapse terminals and can even be a combination such as glutamate and GABA. A second recent experimental finding is a short-term synaptic plasticity, which depends on postsynaptic depolarization releasing a dendritic transmitter, which affects presynaptic release probability. In this work we are investigating the functional consequences for a synapse if it had both co-release and conditioning depression. If initially the GABA component is larger than the glutamate component, the synapse has an inhibitory net effect. However, if the postsynaptic cell is conditioned, the GABA component will be suppressed yielding an excitatory synapse.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurocomputing - Volumes 65â66, June 2005, Pages 39-45
Journal: Neurocomputing - Volumes 65â66, June 2005, Pages 39-45
نویسندگان
Erik Fransén,