کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9653520 679194 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
High discharge variability in neurons driven by current noise
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر هوش مصنوعی
پیش نمایش صفحه اول مقاله
High discharge variability in neurons driven by current noise
چکیده انگلیسی
Cortical neurons in vivo show a highly irregular spontaneous discharge activity, characterized by a gamma statistics and coefficient of variation around unity. Modelling studies showed that this irregularity is a consequence of the high-conductance state caused by the ongoing activity in the cortical network. Here, we investigate to which extent this high discharge variability can be reproduced in vitro using current noise injection. In agreement with numerical studies, we found that equalizing the time constant of the noisy input with the membrane time constant may lead to an irregular discharge activity which, however, departs from a gamma statistics.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurocomputing - Volumes 65–66, June 2005, Pages 493-498
نویسندگان
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