کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9678769 | 1454374 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Spatial and temporal resolution in cryo-electron microscopy-A scope for nano-chemistry
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
شیمی کلوئیدی و سطحی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
Cryo-electron microscopy has evolved in an established approach to study the structure of bio-colloids. Recent developments in instrumentation and automation, often demanded by life sciences, made cryo-EM a general tool in colloid chemistry. Recently improved instrumentation for vitrification has resulted in reliable and reproducible preparation of specimen in water and other solvents. A dynamic approach, following processes in time is gaining importance and a time resolution up to 1 ms is expected to become general available. With improved instrumentation and automation 3D reconstructions by cryo-EM tomography are becoming routinely accessible. Tomography as such or in conjunction with time resolved microscopy is expected to give new insights in (macro)molecular assembly/disassembly mechanisms and thus become an essential tool in nano-chemistry.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Colloid & Interface Science - Volume 10, Issues 5â6, December 2005, Pages 245-249
Journal: Current Opinion in Colloid & Interface Science - Volume 10, Issues 5â6, December 2005, Pages 245-249
نویسندگان
P.M. Frederik, N. Sommerdijk,