کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9776396 | 1509485 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
DNA sensor based on functionalized polypyrrole
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A novel DNA sensor based on a functionalized polypyrrole was prepared. The sensor film was obtained by electrocopolymerizing poly(pyrrole-co-4-(3-pyrrolyl) butanoic acid) onto which an NH2-ODN probe was grafted. The obtained sensor is a simple, label-free DNA sensor with direct electrical read-out. Hybridisation with complementary ODN was investigated by observing changes in die cyclic voltammogram and the AC impedance spectrum. Significant modifications of both the voltammogram and AC impedance spectrum were observed when the sensor was incubated in the presence of complementary ODN. The AC impedance spectra show an increased charge transfer resistance of the film after hybridisation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Synthetic Metals - Volume 152, Issues 1â3, 20 September 2005, Pages 37-40
Journal: Synthetic Metals - Volume 152, Issues 1â3, 20 September 2005, Pages 37-40
نویسندگان
Jadranka Travas-Sejdic, Hui Peng, Paul A. Kilmaitin, Mark B. Cannell, G.A. Bowmaker, Ralph P. Cooney, Christian Soeller,