کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9818180 | 1518777 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A single-particle/single-cell microbeam based on an isotopic alpha source
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
سطوح، پوششها و فیلمها
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
A single-cell/single-particle microbeam has been designed in which the radiation source is a high specific-activity alpha-particle emitting radioisotope, rather than a particle accelerator. The source is imaged at the focal point of a compound magnetic lens array. A novel precision microscope stage with an extremely compact design is included with the endstation's locating, targeting and imaging system. This arrangement allows a 4 m long vertical beamline without any bending magnets. The permanent magnet lens design is derived from an electrostatic lens used in our laboratory in an accelerator-based microbeam. The stand-alone microbeam is expected to produce a 10 μm diameter beam, and will serve as a high-end instrument in a biology laboratory, to precisely deposit ionizing radiation damage within single cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms - Volume 231, Issues 1â4, April 2005, Pages 207-211
Journal: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms - Volume 231, Issues 1â4, April 2005, Pages 207-211
نویسندگان
G.J. Ross, G. Garty, G. Randers-Pehrson, D.J. Brenner,